What is Avanafil (Stendra)?
Avanafil is used to treat erectile dysfunction in men (also called sexual impotence). Avanafil belongs to a group of medications called phosphodiesterase type 5 inhibitors. These medications prevent an enzyme called phosphodiesterase type 5 from working too quickly. The penis is one of the areas where this enzyme acts.
Erectile dysfunction is a condition in which the penis does not harden or expand when a man is sexually aroused or when he cannot maintain an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to the penis to produce an erection. By controlling the enzyme, avanafil helps maintain an erection after sexual stimulation by increasing blood flow. Without physical action on the penis, as occurs during sexual intercourse, avanafil will not produce an erection.
What is avanafil used for?
Avanafil is commonly used for erectile dysfunction, a condition in which a person has difficulty achieving or maintaining an erection. Avanafil may also be used for other conditions, at the doctor's discretion.
How does avanafil work (mechanism of action)?
Avanafil works by blocking an enzyme in the body called PDE5, which helps relax certain blood vessels. This increases blood flow to the penis during arousal, making it easier to achieve and maintain an erection.
How is avanafil supplied (dose forms)?
Brand names and other names
StendraDosage forms and dosages: 50 mg, 100 mg, 200 mg, oral tablets
What are the most common side effects of avanafil?
The most common side effects of avanafil are listed below. Tell your doctor if you experience any of these side effects that bother you.
HeadacheFlushingRunny or stuffy nose, sore throat, or common cold symptomsBack painOther avanafil side effects not listed here may occur. Consult your doctor if you think you are experiencing a medication-related side effect.
What is the most effective dose of Stendra?
Stendra is available in three standard doses, ranging from 50 mg to 200 mg. The recommended starting dose of Stendra is 100 mg, taken 15 to 30 minutes before sexual intercourse.
Because erectile dysfunction can vary in severity, your doctor will choose the appropriate Stendra dose based on the severity of your symptoms, your age, general health, and other factors.
As with other erectile dysfunction medications, it may take time to determine the correct Stendra dose for you. Your doctor may recommend adjusting your dose if you still have difficulty achieving an erection after using Stendra or if you experience severe or persistent side effects.
How is Stendra different from Viagra?
Although Stendra and Viagra are both designed to treat erectile dysfunction, there are several key differences between the two drugs:
- Stendra is more selective than Viagra, meaning it acts more specifically on the PDE5 enzyme, which is responsible for regulating blood flow to the erectile tissue of the penis.
- Stendra is less likely than Viagra to cause side effects, such as headaches and facial flushing.
- Stendra generally starts working faster than Viagra and is less affected by factors such as food and alcohol consumption.
- Stendra has a slightly longer half-life than Viagra, meaning it remains effective longer after taking it.
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